S-Adenosyl-L-Methionine (SAMe) is a natural compound and methyl group donor that supports the methylation cycle, a process which is essential for many aspects of health. Methylation is fundamental for ridding the body of certain toxins, and certain people, such as those with chronic liver disorders, cannot produce adequate levels of SAMe.

SAMe’s effectiveness to support a balanced mood is demonstrated by many clinical studies. SAMe is in fact so effective for boosting a low mood that it is legally registered as a prescription drug in several European countries for mood balance.  One study showed that SAMe was as effective as a common prescription medication for mood. It is thought that SAMe works by help boosting serotonin, dopamine and melatonin levels in the brain, low levels of which are commonly associated with mood imbalances such as anxiety and depression. SAMe has also been found to support joint health in osteoarthritis patients as effectively as a popular anti-inflammatory drug by reducing inflammation and protecting joint tissue from degradation.

At Five Natural, we do our best to ensure accuracy and up to date product information and product images on our website. Please note that occasionally manufacturing changes to packaging or ingredients may be pending updates on our website.

On occasion, products may ship with different packaging as per recent updates by the manufacturer or supplier. In these instances, although ingredients often remain the same with the exception of updated packaging we strongly recommend that you read all associated labels, warnings and directions before use. Do not rely solely on the information provided on Five Natural's website.

Probiotics are kept refrigerated in our warehouse. Probiotics will ship with a free ice pack. The product may not be cold upon delivery but the ice pack helps maintain a cool temperature throughout transit, consider weekend delays when ordering.