I tried this to help with the horrible menopause mood swings I was struggling with and it has finally made me feel like myself again. Thank goodness I finally found the answer to help me feel normal, as menopause has been HELL for me. I started with 200 mg 1 time a day and after a week started feeling better, so I took a second pill to see if I would feel even better, but it had the opposite affect and it gave me anxiety. I decided to stay with one pill a day and I kept feeling better and better every week. its been a couple months now and I am back to feeling happy and calm and NORMAL!!!! Its amazing that one little supplement tablet can make such a huge difference in my life. I wish I would have found this a year ago and it would have saved me a lot of struggle. I tried everything from hormone therapy to tons of supplements suggested for menopause which helped with the hot flashes and night sweats, but nothing helped me to feel happy again until SAMe, it also helped with my libido which is wonderful and it has helped with reducing chronic pain from a car accident. Its also supposed to be good for your liver, which is fantastic. I do not notice any negative side effects at the 200 mg dose. I am so glad I tried this supplement and plan to continue to take it. If you are reading this review and are searching for help, I hope you find the answer to make you feel good again.

Day 20 review. I rarely write reviews for products but I'm amazed at how well this stuff works. The pandemic has had an impact on my mental health and it finally reached a point where I was seeking out help. I have taken ssri's in the past and they do work but I found the side effects to be a bit much. I have taken Sam-e in the past but never had much success but after some additional research I figured I'd give it another go. Consistency is key to knowing if this will work for you or not. Take it at the same time daily for a couple weeks and make sure your getting 7+ hours of sleep at night.**A word of caution to anyone who's currently taking ssri's, microdosing psychedelics or recreationally taking drugs that affect serotonin. Sam-e is known to work on serotonin in the body, mixing these drugs with Sam-e can be dangerous and can potentially cause serotonin syndrome. Talk to your doctor first and/or stop taking the other drugs well before trying Sam-e. **I take only 200mg of sam-e first thing in the morning on an empty stomach with some caffeine (200mg rapid release + 100mg extended release) and a 21 mg nicotine patch (New Years resolution to quit vaping). I don't eat for the next 30 minutes to an hour. I store Sam-e in the fridge and take it with water.It has a subtle effect to it that is recognizable to people who have taken drugs that affect serotonin. There is some stomach discomfort but that's to be expected and not as bad as some make it out to be (mine might be caused my the caffeine on an empty stomach and your stomach also has many serotonin receptors). The most noticeable difference has been my quality of sleep, it's improved dramatically. My depression and anxiety have also improved to a manageable level. I work a physically job and have noticed some pain relief in my joints. It's been an overall positive experience.It's important to keep your expectations reasonable. It's not a magic pill that will make you super happy but it can give you some control back of your negative emotions. You'll still have bad days but they won't be quite as bad. This is my experience so far, your mileage may vary. Some people might need 400mg but I would try just 200mg first and see how it goes. It's important to keep your dosing consistent and also the way you dose (not eating with the food). I refrigerate mine because I read that it was recommended to prevent oxidation of the drug (not sure if it's true or not but it can't hurt).Overall I look forward to taking Sam-e in the morning. It's helped me significantly. This is the brand I've taken. The capsules have no flavor and might be “large” for some but I have never had an issue taking them. If your curious about the effectiveness of Sam-e, check out pubmed to get some unbiased research. Good luck!

This product is a game-changer when it comes to supporting methylation, a fundamental process for various aspects of health. SAMe, a natural compound, serves as a vital methyl group donor, crucial for toxin elimination. It's particularly valuable for individuals with chronic liver disorders who may struggle to produce sufficient SAMe. This supplement has made a noticeable difference in my overall well-being.

Very cheap compared to walmart. Works well!