Pantethine is the active form of vitamin B5 or pantothenic acid. Supplementing with regular pantothenic acid will not necessarily increase the body’s levels of pantethine since this conversion process is tightly regulated. Pantethine is involved in hundreds of metabolic processes including energy production and fatty acid synthesis. It regulates the production of total cholesterol, triglycerides, LDL, and HDL, supporting healthy cholesterol balance, a role that is not shared by pantothenic acid. Pantethine is also required for the synthesis of stress hormones in the adrenal glands, therefore an inadequate supply may result in adrenal insufficiency, which compromises immunity, energy, metabolism and overall well-being. Lastly, it is also essential for phase II liver detoxification and may protect against fatty liver degeneration and other types of liver damage better than regular vitamin B5.

At Five Natural, we do our best to ensure accuracy and up to date product information and product images on our website. Please note that occasionally manufacturing changes to packaging or ingredients may be pending updates on our website.

On occasion, products may ship with different packaging as per recent updates by the manufacturer or supplier. In these instances, although ingredients often remain the same with the exception of updated packaging we strongly recommend that you read all associated labels, warnings and directions before use. Do not rely solely on the information provided on Five Natural's website.

Probiotics are kept refrigerated in our warehouse. Probiotics will ship with a free ice pack. The product may not be cold upon delivery but the ice pack helps maintain a cool temperature throughout transit, consider weekend delays when ordering.